Extracts of Alangium salviifolium (L. f.) Wanger in bark have been locally used in Meche Community of Jhapa district by the old and traditional practitioner for the treatment of Diarrhoea, piles and vomiting.etc. Hexane, Dichloromethane, ethylacetate, methanol and 50% aqueous methanol bark extract of A. salviifolium were undertaken for the investigation of phytochemical screening and antibacterial activity. The test organisms were diagnostic laboratory isolates: